Conocimientos y prácticas sobre sífilis materna y congénita en adolescentes embarazadas en un Hospital General de Paraguay: estudio cualitativo

Introducción: La sífilis en embarazadas, sigue siendo un gran problema de salud pública en todo el mundo, y en Paraguay, no es la excepción. La sífilis congénita puede provocar abortos, muertes fetales y neonatales, peso bajo al nacer, prematuridad y otras anomalías congénitas, el conocimiento general de la población en edad fértil es fundamental. Objetivo: Analizar los conocimientos y prácticas sobre sífilis materna y sífilis congénita en adolescentes embarazadas en un Hospital General de Paraguay. Metodología: Se realizó un estudio cualitativo, fenomenológico descriptivo. Para la recolección de datos se utilizó la entrevista, simple que fue grabada con previa autorización del participante, la conclusión y recomendación serán entregados a la institución y a las adolescentes embarazadas. Resultados: Participaron diez adolescentes, en su mayoría de 19 años de edad, cinco conocen que la sífilis se transmite a través de las relaciones sexuales, sin embargo, desconocen acerca de cómo se transmite la sífilis congénita. Cinco de las adolescentes menciona haber iniciado las relaciones sexuales a los 16 años. Dos adolescentes a los 15 años, dos a los 14 años y una a los 17 años, nueve de las adolescentes embarazadas mencionan acudir a sus controles prenatales de forma periódica. Dos aún no se han realizado el test de VDRL. Discusión: Se concluye en cuanto al conocimiento, que solo cinco de diez adolescentes conocen acerca de la sífilis, sin embargo, no conocen sobre la sífilis congénita. En cuanto a las prácticas preventivas, 10 acuden de forma periódica a sus controles prenatales.

Introduction: Syphilis in pregnant women continues to be a major public health problem throughout the world, and in Paraguay, it is no exception. Congenital syphilis can cause abortions, fetal and neonatal deaths, low birth weight, prematurity, and other congenital anomalies; general knowledge of the population of childbearing age is essential. Objective: To analyze the knowledge and practices about maternal syphilis and congenital syphilis in pregnant adolescents in a General Hospital in Paraguay. Methodology: A qualitative, descriptive phenomenological study was carried out. A simple interview was used to collect data, which was recorded with prior authorization from the participant. The conclusion and recommendation will be delivered to the institution and to the pregnant adolescents. Results: Ten adolescents participated, mostly 19 years of age, five know that syphilis is transmitted through sexual relations, however, they do not know how congenital syphilis is transmitted. Five of the adolescent's mention having started sexual relations at the age of 16. Two adolescents at 15 years old, two at 14 years old and one at 17 years old, nine of the pregnant adolescent's mention attending their prenatal check-ups periodically. Two have not yet been tested for VDRL. Discussion: It is concluded in terms of knowledge that only five out of ten adolescents know about syphilis; however, they do not know about congenital syphilis. Regarding preventive practices, 10 attend their prenatal check-ups periodically.

Salud en la Frontera: Desafíos y Oportunidades para el Bienestar de las Comunidades Fronterizas

La salud en la frontera presenta una serie de desafíos y oportunidades para el bienestar de las comunidades fronterizas. Estas zonas geográficas, donde los límites políticos y territoriales se entrelazan, enfrentan problemas de salud únicos que requieren enfoques innovadores y colaborativos. Uno de los desafíos principales es el acceso limitado a servicios de atención médica de calidad. Las comunidades fronterizas a menudo carecen de infraestructuras de salud adecuadas, incluyendo hospitales y clínicas, lo que dificulta el acceso a servicios esenciales. Además, las barreras lingüísticas y culturales pueden dificultar aún más la comunicación entre los proveedores de salud y los pacientes, lo que limita la calidad de la atención. A pesar de estos desafíos, también existen oportunidades para mejorar la salud en la frontera. La colaboración transfronteriza puede ser una herramienta poderosa para abordar los problemas de salud comunes. Los países vecinos pueden compartir recursos, conocimientos y mejores prácticas para fortalecer los sistemas de salud en ambos lados de la frontera. Esto incluye la promoción de la formación y capacitación conjunta de profesionales de la salud, el intercambio de información epidemiológica y la armonización de políticas de salud. Además, las comunidades fronterizas pueden aprovechar su diversidad cultural y su conocimiento tradicional para mejorar la atención médica.

Border health presents a series of challenges and opportunities for border communities' well-being. These geographic areas, where political and territorial boundaries are intertwined, face unique health issues that require innovative and collaborative approaches. One of the main challenges is limited access to quality health care services. Border communities often lack adequate health infrastructure, including hospitals and clinics, which makes it difficult to access essential services. In addition, language and cultural barriers can further hinder communication between healthcare providers and patients, thereby limiting the quality of care. Despite these challenges, there are opportunities to improve border health. Cross-border collaboration can be a powerful tool for addressing common health problems. Neighboring countries can share resources, knowledge, and best practices to strengthen their health systems on both sides of their borders. This includes the promotion of joint education and training of health professionals, exchange of epidemiological information, and harmonization of health policies. In addition, border communities can take advantage of cultural diversity and traditional knowledge to improve healthcare.

Mortalidad intrahospitalaria de pacientes con COVID-19 complicados con neumonías bacterianas en asistencia respiratoria mecánica en Cuidados Intensivos de Adultos en un Hospital del Paraguay / In-hospital mortality of patients with COVID-19 complicated by bacterial pneumonia on mechanical ventilation in Adult Intensive Care in a Hospital in Paraguay

Introducción: los pacientes con COVID-19 ingresan en mayor proporción a asistencia respiratoria mecánica, aumentando: el riesgo de neumonía asociada a ventilador (NAV) las tasas de mortalidad, los días de permanencia en las unidades de terapia intensiva (UCI) y los costos sanitarios. Objetivo: determinar la Mortalidad intrahospitalaria de pacientes con COVID-19 complicados con neumonías bacterianas en asistencia respiratoria mecánica en Cuidados Intensivos de Adultos en un Hospital del Paraguay durante los años 2020 a 2021. Metodología: estudio analítico de tipo cohorte retrospectiva. Se registraron variables demográficas, comorbilidades, puntajes en scores de gravedad como el APACHE II al ingreso, la cifra más baja de oxigenación durante la internación expresado por la PaO2 / FIO2, días de ventilación, colocación en decúbito prono, traqueotomía, medidas terapéuticas farmacológicas y no farmacológicas, días de internación, así como las complicaciones y la mortalidad. Resultados: fueron incluidos 214 pacientes, 135 ingresaron a asistencia respiratoria mecánica (ARM) de los cuales 58 (42,9 %) desarrollaron NAV, con edad mediana de 52 años (40-60). Los microorganismos de NAV fueron cocos Gram negativos en 98,3 %, incluyendo Acinetobacter baumanii en 46,5 %, Klebsiella pneumoniae en 22,8 %, Pseudomona aeruginosa en 15,5 % y 5,2 % Stenotrophomona maltofilia. La mortalidad intrahospitalaria fue del 44,8 %. Los menores de 50 años tienen una sobrevida mayor que los mayores (34 días vs 22 días, con p de 0,026). Conclusión: la mortalidad intrahospitalaria fue del 44,8 %. La edad fue un factor de riesgo independiente para la mortalidad en pacientes con NAV, por lo que los profesionales de la salud deben estar atentos a la posibilidad de NAV en pacientes que requieren asistencia respiratoria mecánica, especialmente en pacientes mayores de 50 años.

Introduction: patients with COVID-19 are more likely to require mechanical ventilation, which increases the risk of ventilator-associated pneumonia (VAP), mortality rates, length of stay in intensive care units (ICUs), and healthcare costs. Objective: to determine the in-hospital mortality of patients with COVID-19 complicated by bacterial pneumonia on mechanical ventilation in Adult Intensive Care in a Hospital in Paraguay during the years 2020 to 2021. Methodology: this is a retrospective cohort analytical study. Demographic variables, comorbidities, severity scores such as APACHE II on admission, the worst oxygenation during hospitalization expressed by PaO2/FiO2, days of ventilation, prone position, tracheostomy, pharmacological and non-pharmacological therapeutic measures, days of hospitalization, as well as complications and mortality were recorded. Results: a total of 214 patients were included, 135 were admitted to mechanical ventilation (MRA), of which 58 (42.9%) developed VAP, with a median age of 52 years (40-60). VAP microorganisms were Gram-negative cocci in 98.3%, including Acinetobacter baumanii in 46.5%, Klebsiella pneumoniae in 22.8%, Pseudomona aeruginosa in 15.5%, and Stenotrophomona maltophilia in 5.2%. In-hospital mortality was 44.8%. Those under 50 years of age have a longer survival than those older (34 days vs. 22 days, with p of 0.026). Conclusion: the overall mortality rate was 44.8%. Age was an independent risk factor for mortality in patients with VAP, so healthcare professionals should be aware of the possibility of VAP in patients who require mechanical ventilation, especially in patients over 50 years of age.

Development validation and evaluation of the knowledge test on cardiopulmonary resuscitation and correct use of the automated external defibrillator in Asunción 2023 / Desarrollo validación y evaluación de la prueba de conocimientos sobre reanimación cardiopulmonar y uso correcto del desfibrilador externo automático en Asunción 2023

Introduction: in out-of-hospital cardiac arrest, early and efficient intervention through cardiopulmonary resuscitation (CPR) maneuvers and the use of the automated external defibrillator (AED) are the cornerstone for survival. Instruments that improve education would increase the responsiveness of lay personnel. Objectives: to develop, validate and evaluate a knowledge test on cardiopulmonary resuscitation and correct use of the automated external defibrillator in Asunción during 2023. Methodology: observational cross-sectional study, non-probabilistic sample for convenience of lay personnel users of mass attendance centers in Asunción. An exclusive questionnaire was developed on knowledge in cardiopulmonary resuscitation and the use of the automated external defibrillator (KOR-AED) based on the chain of survival in out-of-hospital cardiac arrest. Content, construct, and internal consistency were validated using expert opinion, factor analysis and Cronbach's alpha. Results: a total of 200 lay people participated, mostly shopping mall customers, with a predominance of men (63.5 %) (127), between 25-29 years old 28.5% (57). 61.5 % (123) had a university education, 75.5 % (151) had not related to health, 52 % (104) had prior knowledge of CPR, but 81.5 % (163) did not. The test showed reliability and suitability for factor analysis (Cronbach's alpha 0.75, Kaiser-Meyers-Olkin; 0.78, Bartlett p<0.05). The questions covered the first three links in the chain of survival, with items of medium to high difficulty. Women performed significantly better (p=0.04). Conclusion: the KOR-AED test is a valid and reliable instrument to improve the education of the layperson in CPR and use of the AED based on the chain of survival.

Introducción: en la parada cardíaca extrahospitalaria la actuación precoz y eficiente mediante maniobras de reanimación cardiopulmonar (RCP) y uso del desfibrilador externo automático (DEA) constituyen la piedra angular para la supervivencia. Instrumentos que mejoren la educación aumentarían la respuesta del personal lego. Objetivos: desarrollar, validar y evaluar una prueba de conocimientos sobre reanimación cardiopulmonar y uso correcto del desfibrilador externo automático en Asunción durante el 2023. Metodología: estudio observacional corte transversal, muestro no probabilístico por conveniencia de personal lego usuarios de centros de concurrencia masiva de Asunción. Se desarrolló un cuestionario exclusivo sobre conocimientos en reanimación cardiopulmonar y uso del desfibrilador externo automático (COR-DEA) basado en la cadena de supervivencia en parada cardíaca extrahospitalaria. Se validó el contenido, el constructo y la consistencia interna mediante la opinión de experto, análisis de factores y el alfa de Cronbach. Resultados: participaron 200 legos mayormente clientes de shoppings, predominando hombres 63,5 % (127) entre 25-29 años 28,5 % (57). Con educación universitaria 61,5 % (123), no relacionados con la salud 75,5 % (151), con conocimientos previos en RCP 52 % (104), pero no en DEA 81,5 % (163). El test mostró fiabilidad y adecuación para análisis factorial (Alfa de Cronbach 0.75, Kaiser-Meyers-Olkin; 0.78, Bartlett p<0.05). Las preguntas abarcarón los tres primeros eslabones de la cadena de supervivencia, con ítems de dificultad media a alta. Las mujeres tuvieron significativamente mejor desempeñó (p=0.04). Conclusión: la prueba COR-DEA es un instrumento válido y fiable para mejorar la educación del lego en RCP y uso del DEA basado en la cadena de supervivencia.

Perfil de transmisión del SARS-COV-2 en una región sanitaria del Paraguay

Introducción: La transmisión viral a menudo se propaga en grupos, donde las infecciones se pueden rastrear hasta un caso índice o una ubicación geográfica, para así poder tomar medidas de prevención al respecto. Entender el perfil de transmisión del SARS-CoV-2 es esencial para desarrollar estrategias efectivas de prevención y control de la enfermedad. Objetivo: Determinar el perfil de transmisión del Sars-Cov-2, a partir de clúster con casos índices identificados, en la V región sanitaria (Caaguazu) del Paraguay, entre julio y octubre del 2020. Metodología: Se realizó un estudio observacional, descriptivo, de corte transversal, con fichas de notificación de casos de COVID-19 y resultados laboratoriales de la RT_PCR en pacientes diagnosticados con COVID-19 en la V Región Sanitaria entrejulio y octubre del 2020. Resultados: Fueron identificadas 703 personas con Sars-Cov-2 positivo. El 55,49 % de las personas no reconoció algún nexo de contagio. Con respecto al tipo de evento donde ocurrían con mayor frecuencia los contagios, ocurrieron en Eventos Sociales en 58,14 % de los casos y en el Ambiente Familiar en el 33,89 %. La transmisión secundaria se observó en el 17,40 % de los casos. Fueron identificados 58 Clústers, con una mediana de tamaño de los mismos de 3 (RIQ 2-4), y 267 personas (37,98 %) asociadas a los mismos. Discusión: La mayoría de las personas no reconocieron su nexo de contagio, sin embargo, en los que, si conocieron, se puede observar que la participación en eventos sociales fue el principal nexo, por lo que es fundamental realizar este tipo de ejercicios para hacer el seguimiento oportuno de los casos.

Introduction: Viral transmission often spreads in clusters, where infections can be traced to an index case or a geographic location, in order to take preventive measures in this regard, understanding the transmission profile of SARS-CoV-2 is essential. to develop effective disease prevention and control strategies. Objective: to determine the transmission profile of Sars-Cov-2, from clusters with identified index cases, in the V health region (Caaguazú) of Paraguay, between July and October 2020. Methodology: We carried out an observational, descriptive, cross-sectional study, with notification sheets of COVID-19 cases and laboratory results of the RT_PCR in patients diagnosed with COVID-19 in the V Sanitary Region between July and October 2020. Results: We identified 703 people with positive Sars-Cov-2. 55.49% of people did not recognize any contagion link. Regarding the type of event where infections occurred most frequently, was in Social Events in 58.14% of the cases and the Family Environment in 33.89%, secondary transmission was observed in 17.40% of the cases. 58 Clusters were identified, with a median size of 3 (IQR 2-4), and 267 people (37.98%) associated with them. Discussion: Most of the people did not recognize their contagion link, however, in those who did know, the main link was because they participated in social events, so it is essential to carry out this type of exercise to do timely follow-up. of the cases.

Development validation and evaluation of the knowledge test on cardiopulmonary resuscitation and correct use of the automated external defibrillator in Asunción 2023

Introduction: in out-of-hospital cardiac arrest, early and efficient intervention through cardiopulmonary resuscitation (CPR) maneuvers and the use of the automated external defibrillator (AED) are the cornerstone for survival. Instruments that improve education would increase the responsiveness of lay personnel. Objectives: to develop, validate and evaluate a knowledge test on cardiopulmonary resuscitation and correct use of the automated external defibrillator in Asunción during 2023. Methodology: observational cross-sectional study, non-probabilistic sample for convenience of lay personnel users of mass attendance centers in Asunción. An exclusive questionnaire was developed on knowledge in cardiopulmonary resuscitation and the use of the automated external defibrillator (KOR-AED) based on the chain of survival in out-of-hospital cardiac arrest. Content, construct, and internal consistency were validated using expert opinion, factor analysis and Cronbach's alpha. Results: a total of 200 lay people participated, mostly shopping mall customers, with a predominance of men (63.5 %) (127), between 25-29 years old 28.5% (57). 61.5 % (123) had a university education, 75.5 % (151) had not related to health, 52 % (104) had prior knowledge of CPR, but 81.5 % (163) did not. The test showed reliability and suitability for factor analysis (Cronbach's alpha 0.75, Kaiser-Meyers-Olkin; 0.78, Bartlett p<0.05). The questions covered the first three links in the chain of survival, with items of medium to high difficulty. Women performed significantly better (p=0.04). Conclusion: the KOR-AED test is a valid and reliable instrument to improve the education of the layperson in CPR and use of the AED based on the chain of survival.

Introducción: en la parada cardíaca extrahospitalaria la actuación precoz y eficiente mediante maniobras de reanimación cardiopulmonar (RCP) y uso del desfibrilador externo automático (DEA) constituyen la piedra angular para la supervivencia. Instrumentos que mejoren la educación aumentarían la respuesta del personal lego. Objetivos: desarrollar, validar y evaluar una prueba de conocimientos sobre reanimación cardiopulmonar y uso correcto del desfibrilador externo automático en Asunción durante el 2023. Metodología: estudio observacional corte transversal, muestro no probabilístico por conveniencia de personal lego usuarios de centros de concurrencia masiva de Asunción. Se desarrolló un cuestionario exclusivo sobre conocimientos en reanimación cardiopulmonar y uso del desfibrilador externo automático (COR-DEA) basado en la cadena de supervivencia en parada cardíaca extrahospitalaria. Se validó el contenido, el constructo y la consistencia interna mediante la opinión de experto, análisis de factores y el alfa de Cronbach. Resultados: participaron 200 legos mayormente clientes de shoppings, predominando hombres 63,5 % (127) entre 25-29 años 28,5 % (57). Con educación universitaria 61,5 % (123), no relacionados con la salud 75,5 % (151), con conocimientos previos en RCP 52 % (104), pero no en DEA 81,5 % (163). El test mostró fiabilidad y adecuación para análisis factorial (Alfa de Cronbach 0.75, Kaiser-Meyers-Olkin; 0.78, Bartlett p<0.05). Las preguntas abarcarón los tres primeros eslabones de la cadena de supervivencia, con ítems de dificultad media a alta. Las mujeres tuvieron significativamente mejor desempeñó (p=0.04). Conclusión: la prueba COR-DEA es un instrumento válido y fiable para mejorar la educación del lego en RCP y uso del DEA basado en la cadena de supervivencia.

Association between the use of Sci-Hub and consultation of scientific journals by medical students from six Latin American countries: A secondary analysis.

Introduction and objective: Sci-Hub is a website that allows users to download full-text versions of millions of scientific articles for free. The objective of this study was to evaluate the association between the use of Sci-Hub and consultation of scientific journals by medical students from six Latin American countries. Methods: We conducted a secondary analysis of data from a 2017 cross-sectional study of medical students from six Latin American countries (Argentina, Bolivia, Chile, Colombia, Paraguay, and Peru). Consultation of scientific journals was considered as the dependent variable, while the independent variable was the use of Sci-Hub. Responses were categorized as: "do not know"; "did not use it"; "used it at least once a week"; "used it more than once a week"; and "used it every day of the month". In simple and multiple regression analyses, multivariate random-effects models were used to estimate prevalence ratios (PR), with 95% confident intervals (CI). Results: Of the 6632 participants, 38.2% consulted scientific journals and 10.3% used Sci-Hub once a week. Using Sci-Hub at least once a week was associated with a 20% increase in the prevalence of consulting scientific journals (PR: 1.20, 95% CI: 1.10-1.31, p < 0.001). The variables positively associated with Sci-Hub use included being in the sixth year of medical school (PR: 2.34), affiliation to more than one academic research group (PR: 1.81), being a medical student in Colombia (PR: 1.63), intermediate (PR: 1.16) and advanced levels of English (PR: 1.23), and daily use of PubMed (PR: 1.66), SciELO (PR: 1.87), and/or SCOPUS (PR: 1.58). Conclusion: Amongst medical students surveyed from the above six Latin American countries, the use of Sci-Hub at least once a week was significantly associated with the self-reported prevalence of consulting scientific journals.

Percepción sobre el maltrato en médicos residentes de un Hospital de referencia de Paraguay

Introducción: El maltrato es una problemática que el mundo viene sufriendo y sosteniendo desde siglos anteriores y el sector salud no queda exento de tal agravio. En Latinoamérica existe un alto índice de maltratos en médicos. Objetivos: Determinar la percepción sobre el maltrato en médicos residentes de un hospital de referencia nacional de Paraguay durante el 2020. Materiales y métodos: Se realizó un estudio observacional, descriptivo de corte transversal, dónde fueron incluidos 240 residentes de las diferentes especialidades de un hospital de referencia nacional. Resultados: Ingresaron al estudio 240 médicos residentes, con una edad promedio de 27,3 ±1,6. El 52,08% (125) fueron del sexo masculino. En cuanto al maltrato psicológico, el 98,33% (236) recibió críticas o humillaciones, el 92,08% (221) ha sido víctima de gritos y el 39% (94) de guardia como castigo. Lo que respecta al maltrato físico, el 9% (22) de los residentes recibió golpes o empujones. El 7,92% (19) refirió haber recibido comentarios sexuales sobre su cuerpo o parte de él y el 2% (5) haber sido expuesto a material pornográfico, evidenciando el maltrato de índole sexual. En relación al perpetrador del total de episodios de maltrato que corresponde al 56,78% (494), el Residente Superior ha sido señalado como principal autor. Conclusión: Existe una alarmante frecuencia de maltrato en la formación profesional de los médicos residentes. Se destaca el maltrato psicológico en mayor proporción y al Residente Superior como principal perpetrador.

Introduction: Abuse is a problem that the world has been suffering and sustaining for centuries and the health sector is not exempt from such injury. In Latin America there is a high rate of mistreatment in doctors. Objectives: To determine the perception of mistreatment in resident doctors of a national reference hospital in Paraguay during 2020. Materials and methods: Cross-sectional study was carried out, where 240 residents of the different specialties of a national referral hospital were included. Results: 240 residents entered the study, with a mean age of 27.3 ± 1.6. 52.08% (125) were male. Regarding psychological abuse, 98.33% (236) received criticism or humiliation, 92.08% (221) have been the victim of shouting and 39% (94) on duty as punishment. Regarding physical abuse, 9% (22) of the residents received blows or shoves. 7.92% (19) reported having received sexual comments about their body or part of it and 2% (5) having been exposed to pornographic material, evidencing abuse of a sexual nature. In relation to the perpetrator of the total abuse episodes, which corresponds to 48.85% (594), the Senior Resident has been identified as the main author. Conclusion: There is an alarming frequency of abuse in the professional training of resident doctors. Psychological abuse stands out in a greater proportion and the Senior Resident as the main perpetrator.

Percepción sobre el maltrato en médicos residentes de un Hospital de referencia de Paraguay / Perception of mistreatment in resident physicians of a reference Hospital in Paraguay

Introducción: El maltrato es una problemática que el mundo viene sufriendo y sosteniendo desde siglos anteriores y el sector salud no queda exento de tal agravio. En Latinoamérica existe un alto índice de maltratos en médicos. Objetivos: Determinar la percepción sobre el maltrato en médicos residentes de un hospital de referencia nacional de Paraguay durante el 2020. Materiales y métodos: Se realizó un estudio observacional, descriptivo de corte transversal, dónde fueron incluidos 240 residentes de las diferentes especialidades de un hospital de referencia nacional. Resultados: Ingresaron al estudio 240 médicos residentes, con una edad promedio de 27,3 ±1,6. El 52,08% (125) fueron del sexo masculino. En cuanto al maltrato psicológico, el 98,33% (236) recibió críticas o humillaciones, el 92,08% (221) ha sido víctima de gritos y el 39% (94) de guardia como castigo. Lo que respecta al maltrato físico, el 9% (22) de los residentes recibió golpes o empujones. El 7,92% (19) refirió haber recibido comentarios sexuales sobre su cuerpo o parte de él y el 2% (5) haber sido expuesto a material pornográfico, evidenciando el maltrato de índole sexual. En relación al perpetrador del total de episodios de maltrato que corresponde al 56,78% (494), el Residente Superior ha sido señalado como principal autor. Conclusión: Existe una alarmante frecuencia de maltrato en la formación profesional de los médicos residentes. Se destaca el maltrato psicológico en mayor proporción y al Residente Superior como principal perpetrador.

Introduction: Abuse is a problem that the world has been suffering and sustaining for centuries and the health sector is not exempt from such injury. In Latin America there is a high rate of mistreatment in doctors. Objectives: To determine the perception of mistreatment in resident doctors of a national reference hospital in Paraguay during 2020. Materials and methods: Cross-sectional study was carried out, where 240 residents of the different specialties of a national referral hospital were included. Results: 240 residents entered the study, with a mean age of 27.3 ± 1.6. 52.08% (125) were male. Regarding psychological abuse, 98.33% (236) received criticism or humiliation, 92.08% (221) have been the victim of shouting and 39% (94) on duty as punishment. Regarding physical abuse, 9% (22) of the residents received blows or shoves. 7.92% (19) reported having received sexual comments about their body or part of it and 2% (5) having been exposed to pornographic material, evidencing abuse of a sexual nature. In relation to the perpetrator of the total abuse episodes, which corresponds to 48.85% (594), the Senior Resident has been identified as the main author. Conclusion: There is an alarming frequency of abuse in the professional training of resident doctors. Psychological abuse stands out in a greater proportion and the Senior Resident as the main perpetrator.

Discrimination, stigma and mental health: what's next?

Stigma and discrimination are a major ongoing problem in the field of mental health as these impact on patient outcomes, access to and acceptability of therapeutic interventions, their quality of life, general wellbeing, social inclusion and opportunities. Social stereotypes, culture and prejudices all contribute to continuing discrimination in mental health. Different settings where people function may also be sources of discrimination such as work and educational environments. The lack of knowledge and understanding of mental health/illness by individuals, their families, carers and policymakers as well as the social media reporting also impact on social attitudes to discrimination. It has been also described a relevant impact of stigma among specific social minorities reporting poor mental health such as elderly people, youths, sexual variants, persons with disability. Educational programs, raising awareness trainings and proper public policies may be developed in order to reduce stigma at social level with favourable outcomes for people with mental illness.

Intergenerational sex and early sexual debut are associated with HIV infection among transgender women in Paraguay.

INTRODUCTION: HIV prevalence among transgender women is high worldwide. The objectives of the present study were to estimate the current prevalence of HIV and identify factors associated with high HIV burden among transgender women in Paraguay. METHODS: Transgender women aged ≥15 years in four regions of Paraguay were recruited by Starfish sampling between February and March 2021. RESULTS: In total, 322 transgender women were included. Mean age was 31 years (range 15-67), and 102 had positive HIV test results (31.7%, 95% confidence interval [CI] 26.6-37.1). In multivariable analysis, factors associated with HIV infection were age at first intercourse ≤17 years (adjusted odds ratio [aOR] 5.47; 95% CI 1.05-28.42), >10 years difference in age with the last sexual partner (aOR 1.60; 95% CI 1.04-2.46), substance use (mostly cocaine) (aOR 3.00; 95% CI 1.47-6.12), higher risk perception (aOR 3.08; 95% CI 1.53-6.17), not testing for HIV (aOR 1.23; 95% CI 1.09-1.39), and accessed by a peer educator (aOR 3.86; 95% CI 1.77-8.38). CONCLUSIONS: Sexual debut as a minor and a large age difference with sexual partners are associated with high burden of HIV among transgender women in Paraguay. Our study corroborates the finding of cocaine use during sex as a risk factor for HIV. Prevention programmes must address structural and social vulnerabilities to stem the tragically high burden of HIV among transgender women.

Frecuencia y factores de riesgo para la hipoglucemia neonatal en un hospital regional, 2021

Introducción: La hipoglucemia que es la reducción en la concentración de glucosa de la sangre en circulación, es un trastorno metabólico común en el recién nacido (RN), sobre todo en aquellos que tienen factores predisponentes como bajo peso al nacer, grande para la edad gestacional, pretérmino, dificultad respiratoria, sepsis, diabetes e hipertensión materna y otros menos frecuentes. Objetivos: analizar la frecuencia de la hipoglucemia y su relación con los factores de riesgo en Recién Nacidos (RN), del Hospital Regional de Encarnación en el año 2021. Metodología: estudio observacional, descriptivo de corte trasversal con componente analítico, en niños del alojamiento conjunto del Servicio de Neonatología del Hospital Regional de Encarnación, de abril a junio del 2021. Fueron incluidos aquellos en los que, por presentar algún factor de riesgo se determinó el nivel de glucosa en sangre capilar con tira reactiva y glucómetro. Resultados: los RN nacieron por cesárea en el 70%, control prenatal insuficiente en el 8,2% sexo masculino el 57%, pretérmino 25%, Apgar bajo 1,18%, dificultad respiratoria 11%, bajo peso al nacer 17%, grande para la edad gestacional 35% Las madres presentaron diabetes gestacional en el 22% e hipertensión materna en el 12%. Los factores de riesgo de riesgo se presentaron en 21,8% e incidencia de hipoglucemia en 4,1%. Conclusión: En los 774 niños que nacieron en ese periodo, la frecuencia de hipoglucemia fue menor a la citada en la literatura. El análisis se realizó mediante las pruebas estadísticas de Fischer y los factores de riesgo relacionados en forma estadísticamente significativa (p=0.05), fueron el control prenatal insuficiente, hipertensión materna, diabetes gestacional, prematuridad y los pequeños para la edad gestacional.

Introduction: Hypoglycemia, which is the reduction in the concentration of glucose in the circulating blood, is a common metabolic disorder in the newborn (NB), especially in those who have predisposing factors such as low birth weight, large for age gestational, preterm, respiratory distress, sepsis, maternal diabetes and hypertension and other less frequent risk factors. Objectives: to analyze the frequency of hypoglycemia and its relationship with risk factors in Newborns (NBs) at the Encarnación Regional Hospital in the year 2021. Methodology: this was an observational, descriptive cross-sectional study with an analytical component, in children admitted to the rooming-in section of the Neonatology Service of the Encarnación Regional Hospital, from April to June 2021. We included infants who, due to presenting some risk factor, had their capillary glucose level measured with a test strip and a glucometer. Results: 70% of newborns were born by cesarean section, 57% were males 8.2% had insufficient prenatal care, 25% were preterm, low Apgar scores were present in 1.18%, respiratory distress in 11%, low birth weight in 17%, large for gestational age in 35%. Maternal gestational diabetes was present in 22% and maternal hypertension in 12%. Risk factors were present in 21.8% and the incidence of hypoglycemia was 4.1%. Conclusion: In the 774 children who were born during this period, the frequency of hypoglycemia was lower than that cited in the literature. The analysis was carried out using Fischer's statistical tests and the related risk factors in a statistically significant way (p=0.05) were insufficient prenatal control, maternal hypertension, gestational diabetes, prematurity and small for gestational age.

HIV drug resistance in persons initiating or reinitiating first-line antiretroviral therapy in Paraguay: Results of a National Patient Survey.

Human immunodeficiency virus (HIV) drug resistance increases mortality and morbidity and antiretroviral therapy (ART) costs. We describe Paraguay's first nationally representative survey on pretreatment drug resistance (PDR) conducted among persons who initiated or reinitiated ART in 2019. ​​​​We conducted a cross-sectional survey of antiretroviral (ARV) drug resistance in Paraguay in 2019. Participants were sampled at four comprehensive care clinics where 90% of patients with HIV in Paraguay initiate ART. Patients included were adults ≥18 years old who initiated first-line ART or reinitiated the same first-line ART regimen after ≥3 months of discontinuation. Of 208 patients, 93.8% had no prior ART exposure, 3.8% reinitiated the same regimen, 2.4% had unknown prior ART exposure; and 31.3% had a CD4 count <200 cells/µl. Mutations associated with resistance were present in 15.4% of patients. Mutations associated with resistance to nonnucleoside reverse transcriptase inhibitors (NNRTI) were present in 13.0% of patients, nucleoside reverse transcriptase inhibitors in 4.3%, and integrase inhibitors in 3.4%. Mutations associated with resistance to tenofovir were present in 1.0% of patients and emtricitabine/lamivudine in 1.4%. ​​Nearly one in six patients had PDR in Paraguay's first nationally representative sample. High NNRTI PDR prevalence underscores the need to accelerate the transition to dolutegravir-based first-line ART. The low PDR prevalence of tenofovir and emtricitabine is reassuring as these ARVs are part of the World Health Organization (WHO)-recommended oral pre-exposure prophylaxis regimen. The high proportion of individuals initiating ART at a late disease stage highlights the need to improve treatment linkage strategies and implement WHO rapid ART initiation recommendations.

"Coronaphobia" in Paraguay: Spanish Validation of the COVID-19 Phobia Scale.

BACKGROUND: The COVID-19 is a highly transmissible disease caused by a new zoonotic coronavirus called SARS-CoV-2 that has led to several health, social, and economic issues worldwide. Anxiety and stress are predominant symptoms in the population during the quarantine; also, levels of fear or phobia have been reported. SUBJECTS AND METHODS: This study validate the Spanish version of the COVID-19 Phobia Scale (C19P-S). Participants were recruited using an Internet-based survey. The survey was open from July 20 to July 31, 2021 and 1079 subjects were included. RESULTS: Kaiser-Meyer-Olkin test was adequate (KMO=0.956) and sphericity tested significantly (p<0.0001). The model of adjustment was good as shown by fit indices (S-B χ2=351.67, df=164, p>0.05; RMSEA=0.033; SRMSR=0.042; CFI=0.995, NFI=0.990). CONCLUSIONS: This confirms that the model of the Spanish version of the C19P-S may reproduce the same four-factors model from the original version of the scale and all items of these factors reported standardized loadings higher than 0.40 (p<0.001).

Caracterización de niños y adolescentes con Fibrosis Quística que acuden a un hospital de IV Nivel de Atención del Seguro Social de Paraguay, años 2016 a 2019

RESUMEN Introducción: La fibrosis quística es una enfermedad que afecta a múltiples sistemas del organismo tanto de niños como de adultos. Constituye el trastorno genético limitante más frecuente de los caucásicos. Objetivo: Caracterizar a los pacientes con fibrosis quística (FQ)internados en el Servicio de Pediatría de un Hospital de IV Nivel de Atención del Seguro Social de Paraguay durante los años 2016 y 2019. Materiales y Métodos: Estudio observacional, descriptivo, de corte transversal, con muestreo no probabilístico, en niños/as que acudieron al Hospital entre los años 2016 y 2019. Se utilizaron las historias clínicas de los pacientes ingresados, que cumplieron con los criterios de inclusión. Resultados: Fueron incluidos 52 pacientes, 32/52 (61,54%) fueron del sexo femenino. La mediana de edad fue de 3 años (1 mes a 16 años). Del total, 37/52 (71,2%) pacientes no contaba con antecedentes familiares de FQ y el tiempo de diagnóstico que más frecuente fue entre los 0 a 8 meses de edad. La manifestación clínica al momento del diagnóstico que predominó fue la mixta (respiratorio/digestivo) en 38/52 pacientes (73,1%) y el patógeno más comúnmente aislado de secreción traqueal fue la Pseudomona aeruginosa en 33 (63,5%) de ellos. Cursaron con riesgo de desnutrición 18(34,6%) pacientes. Conclusión: Se pudo apreciar un predominio del sexo femenino, siendo la forma clínica de debut predominante la mixta, respiratorio y digestiva. Un tercio de los pacientes se encontraban con riesgo de desnutrición.

ABSTRACT Introduction: Cystic fibrosis is a disease that affects multiple body systems in both children and adults. It is the most common limiting genetic disorder in Caucasians. Objective: To characterize patients with cystic fibrosis (CF) hospitalized in the Pediatric Service of a Level IV Social Security Hospital in Paraguay during 2016-2019. Materials and Methods: this was an observational, descriptive and cross-sectional study, with non-probabilistic sampling, in children who presented to the Hospital between 2016 and 2019. The medical records of admitted patients who met the inclusion criteria were used. Results: 52 patients were included, 32/52 (61.54%) were female. The median age was 3 years (1 month to 16 years). Of the total, 37/52 (71.2%) patients did not have a family history of CF and the most frequent time of diagnosis was between 0 and 8 months of age. The predominant clinical manifestation at the time of diagnosis was mixed (respiratory/digestive) in 38/52 patients (73.1%) and the most commonly isolated pathogen from tracheal secretions was Pseudomonas aeruginosa in 33 (63.5%) of them. they. 18 (34.6%) patients were at risk of malnutrition. Conclusion: a predominance of the female sex was observed, the predominant clinical form of debut was mixed, respiratory and digestive. One third of the patients were at risk of malnutrition.